Hypertension, Prescription Drug Copayments, and Drug Therapy Adherence

The Prevalence of Drug-Drug Interaction and Inappropriate Drug Prescription Among the Elderly in Kashan

Background: Drug-drug Interaction (DDI) among the elderly is one of the major healthcare challenges worldwide. The present study assessed the rates of DDI and inappropriate drug prescription among the elderly in Kashan City, Iran.  Methods: This descriptive-analytical study was designed, conducted, and reported according to the guideline of Strengthening the Reporting of Observational Studies ...

Drug Therapy in Patients with Chronic Thromboembolic Pulmonary Hypertension

Background: Chronic Thromboembolic Pulmonary Hypertension (CTEPH) results from the obstruction of predominantly major pulmonary vessels by organized blood clots and is one of the causes of pulmonary hypertension. The disease is still underdiagnosed and the true prevalence is not clear. The objective of this study was to determine the clinical characteristics and current management of patients w...

Adherence to HIV drug therapy.

Antiretroviral therapy has dramatically improved the prognosis for many patients with HIV infection. For many patients who can navigate combinations of drugs and time their doses precisely, these drug regimens typically slow the progression of the disease and lengthen survival. But because these drug regimens are very complex, adherence--the degree to which patients follow medical advice in tak...

Opioid therapy and prescription drug diversion.

Prescription drug monitoring and drug overdose mortality

BACKGROUND Abuse of prescription drugs, particularly opioid analgesics, has become a major source of injury mortality and morbidity in the United States. To prevent the diversion and misuse of controlled substances, many states have implemented prescription drug monitoring programs (PDMPs). This study assessed the impact of state PDMPs on drug overdose mortality. METHODS We analyzed demograph...